CBD, or cannabidiol, is one of the numerous compounds present in the cannabis plant. It has been promoted as an alternative therapy, and even a cure, for a variety of ailments, including cancer, on various internet communities. Furthermore, several cancer patients claim that CBD has helped them manage their symptoms and adverse effects from regular cancer treatment as a supplemental therapy.
Researches on CBD oil for cancer
Many studies related to CBD oil for cancer in the lab employed mice or human cells. As a result, the research is still in its early stages, and more cancer patient studies are needed before definitive findings can be drawn. CBD and cancer research is now concentrated on two areas. First, if CBD can slow or even stop cancer from progressing, and second, whether CBD can relieve some of the side effects of cancer and cancer therapy, such as pain, nausea, and anxiety.
CBD may suppress colorectal cancer cell multiplication, according to a 2014 study that looked at in vivo experimental models of colon cancer. It had no effect on healthy cells. CBD was also found to trigger apoptosis via regulating numerous anti- and pro-apoptotic proteins in a 2019 research, resulting in a decrease in total tumor size.
Breast cancer is the most common cancer in women and the leading cause of death. Cannabinoids have been demonstrated to have a modulatory influence on hormone-sensitive breast cancer cells by interacting with receptor-dependent and independent control of invasion and proliferation, two important hallmarks of cancer progression. CBD has been proven to activate the intrinsic apoptotic pathway in breast cancer cells, resulting in cell death. CBD’s significance in the formation of reactive oxygen species was also discussed in the 2011 study (ROS). Because ROS inhibition limits the activation of autophagy and apoptosis, damaged cells can be cleansed away and sick cells can die, this process is critical.
Another cancer with a high frequency and fatality rate is lung cancer. Ninety percent of lung cancers are caused by tobacco smoking, as well as other factors including chemical exposure or radiation. Cannabinoid receptor expression levels were found to be a possible measure of survival in patients with non-small cell lung cancer in a recent study. CBD was also able to stop lung cancer cells from expressing and growing epidermal growth factor receptors.
Is it safe to use CBD oil for cancer?
You might come across articles online about how CBD might help with cancer therapy or side effects reduction. Please keep in mind that, while such personal anecdotes may be well-intentioned, they are not scientifically validated and do not constitute proof. Large, randomized, controlled clinical trials are still needed to verify the safety and effectiveness of CBD oil for cancer patients.
It’s also worth noting that CBD has been proven in certain studies to interfere with how your body absorbs cancer medications, which is known as a drug interaction. This might make cancer therapies either more hazardous or less effective. More study on these consequences is also required. Because of these risks, you should always consult with your oncologist before using CBD oil for cancer.